Back to homepage Our expertise: Genomics

Master the genomics of your products and processes, to understand and control them- from protocol design to data analysis.

At Smaltis, we harness the power of genomics to support projects requiring the exploration and control of genetic material. We work with all types of samples, from simple to highly complex: cellular or molecular products, clinical and environmental samples, industrial process outputs, diagnostic kits and detection tools, or molecular biology reagents and equipment.
Our two business units – Research Microbiology and Precision Microbiology – work together to secure your genomics projects, whether exploratory or for product and bioprocess validation.

Our offer

Versatile solutions tailored to your needs

Applications 1

SAMPLE CHARACTERIZATION

2

Molecular Effect Evaluation

3

Kits & Reagent Development

4

Bioproduction

Your Needs

Molecular characterization of complex samples

Assessment of product or process impact on molecular targets

Independent validation of molecular biology reagents, devices, or diagnostic kits

Raw material, process, and finished product control for batch release

Our Solutions

→ Nucleic acid extraction
→ Biomarker detection and quantification by qPCR or NGS

→ Study protocol design
→ RNA extraction and reverse transcription
→ Gene expression quantification (RT‑qPCR)

→ Molecular biology platform with diverse technologies

→ Contamination monitoring
→ Genetic stability studies by PFGE and MLST
→ Plasmid linearization studies by qPCR

Our Promise: Rigor and reliability to secure your results

They trust us

Testimonials and references

Laurence RINGENBACH
Cell Biology Lab Manager,
Immunodiagnostic Reagents,
DIACLONE SAS part of Medixbiochemica

Smaltis is a long-term partner with whom we have established a privileged relationship. We work in highly complementary domains and collaborate regularly to provide a comprehensive offering to our clients, utilizing microbiology and molecular biology services that we specifically require. We engage them for services such as sample contamination analysis, production of competent bacteria, and preparation of suspensions of inactivated strains for the development of new monoclonal antibodies. A true bond of trust has developed, facilitated by the geographical proximity of our respective locations and easy communication with their teams, whose flexibility, tenacity in problem-solving, and quality of work are crucial for us.

Jérôme SCHMEISSER and Christelle IACONIS
Biology lab manager
and Scientist
DSM-FIRMENICH

In the context of our developments in animal health dietary supplements, we turned to SMALTIS to assess the impact of our products on the expression of genes of interest in different tissues. The molecular biology expertise of SMALTIS allows us to rely on this laboratory, whose qualitative results provide us with robust and reliable data. We also benefit from constructive exchanges with their teams to progress together throughout the project. SMALTIS thus constitutes a true extension of our R&D department, allowing us to focus on our own expertise while relying on this partner with whom we will continue to collaborate.

Eric ROBINET
Founder and President
LYMPHOBANK

Specialized in the production of cell banks from blood, for research and patient use, we needed to rely on a microbiology company to ensure the absence of contamination in our products from the start of our preparations. Established at the time in the premises of the EFS, it was only natural that we turned to Smaltis, located a few steps from our laboratories. Their work approach and the reliability of their results were exactly what we were looking for, and for several years now, we have entrusted them with all our microbiological analyses. The growth of our respective companies led us to look for new premises... and it is with pleasure that we took over the premises of Smaltis, who then moved into the building just across the street! It is important to have Smaltis in our network of reliable partners with common values, to contribute to the improvement of health!

Pascal MERTENS
R&D Director
CORIS BIOCONCEPT

As part of the development of rapid in vitro diagnostic (IVD) tools for detecting infectious pathologies in humans, we needed to evaluate the performance of new tests dedicated to the detection of bacterial antibiotic resistance mechanisms. We approached Smaltis, a company specializing in microbiology and molecular biology, and found them ideally suited to our needs. Smaltis made its expertise available to assess the efficacy and robustness of our tests on clinical strains with very specific antibiotic resistance profiles, compared with a molecular biology method. The results confirmed the sensitivity, specificity and accuracy of our test, and enabled us to meet regulatory requirements. For us, the Smaltis laboratory is an expert player on whom we can rely to support our developments and obtain the data we need to bring our tools to market.

News and articles

New Offer Structure: 2 Business Units Supporting Your Projects

At Smaltis, our ambition remains unchanged: bringing microbiological excellence to your innovations.
To better address the diversity of your needs, we have structured our offer around 2 complementary Business Units, true pillars of our scientific and technical commitment.

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Malassezia: Cultivating the Invisible – A Challenge Met

Some yeasts are particularly resistant… especially Malassezia restricta.

This lipophilic yeast, naturally present on human skin, is involved in various imbalances of the skin microbiota, notably those linked to dandruff or seborrheic dermatitis. But cultivating it in the laboratory is no easy task!

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Talk and Cheese

Once upon a time was cheese, a high place of communication between fungi and bacteria.

Attracted by the smell of French cheeses, a team from Tufts University published work on how, in Camembert, Roquefort and other festivities, bacteria use compounds produced by fungi and adapt their behavior.

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Viruses at the service of humanity?

Once upon a time, the English bacteriologist Ernest Hankin demonstrated for the first time the presence of anti-bacterial entities in the waters of Indian rivers, putting humanity on the path to a promising anti-infectious therapy that is more relevant than ever.

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ECCMID – ESCMID Global

Smaltis attends the 34th edition of the ECCMID international congress, renamed ESCMID Global, in Barcelona from April 27 to 30, 2024. This clinical microbiology and infectious diseases event is one of the largest and most important congresses in the field of infection, bringing together over 16,000 participants from all over the world to contribute to the dissemination of scientific knowledge.

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Sanofi Vaccines R&D Day

Smaltis attends the Sanofi Vaccines R&D Day, organized by Sanofi in partnership with Lyonbiopôle, Enosis Santé and Polepharma!
This event aims to foster partnerships around 5 themes: antimicrobial approaches, therapeutic vaccines and antibodies, mucosal or skin delivery of vaccines, immunology, and antigen design. Quite a program!

Cédric Muller will be present at this event, which will take place on April 11, 2024, at 14 Espace Henry Vallée in Lyon.

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Microbiota & Health Day 7th edition

Smaltis is delighted to be taking part in the 7th edition of Microbiota & Health Day, organized by Lyonbiopôle and Alliance Promotion Microbiote, on March 26, 2024 in Lyon. The aim of this day is to bring together academic, clinical and industrial players to discuss topical issues that are driving innovation in the field of microbiota and their impact on health.

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AMR Conference 8th edition

Smaltis is happy to participate to the 8th edition of AMR Conference in Basel from March 6th to 7th 2024, a platform for SMEs, start-ups, big pharma, academia, investors and public institutions to discuss strategies and specific challenges faced by the innovation ecosystem in bringing new antimicrobial treatments and diagnostics to the market.

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The same… But better!

The year 2024 marks the 10th anniversary (already!) of the Smaltis adventure! 10 years of microbiology, 10 years of molecular biology, 10 years of passion, 10 years of twists and turns, 10 years of growth, 10 years of self-reflection, 10 years of continuous improvement, 10 years of scientific spirit, 10 years of ambition, 10 years of collaboration, 10 years of human relationships…

It was necessary to celebrate this milestone, and not just by blowing out the candles.

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The Polepharma Microbiomics Days

Smaltis is delighted to have participated in and sponsored, for the fourth consecutive year, the Polepharma Microbiomics Days, held in Rouen on November 22 and 23, 2023.

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